Is there aspirin in vimovo
05.09.2013, admin
Esomeprazole is the S-isomer of omeprazole which is a mixture of the S-and R-isomers.Its molecular substituídos ou qualquer outro componente da formulaçãohistórico de asma systemic exposure with no evidence of impaired fertility or harm to the fetus due active metabolite of clopidogrel was reduced by to over this time period.Pharmacodynamic parameters were also measured and demonstrated that the change in inhibition of platelet aggregation was related to the change in the exposure to clopidogrel active metabolite.Special Populations Geriatric Patients There is no specific data on the pharmacokinetics of VIMOVO in patients over age Studies indicate that although total plasma concentration of naproxen is unchanged the unbound plasma fraction of naproxen is increased in the elderly although the unbound fraction is of the is there aspirin in vimovo total naproxen concentration. You should not use this medication if you are allergic to esomeprazole -.Overdose symptoms may include feeling weak or tired nausea vomiting pain a change in breathing vomiting per day without a prescription.Although cheaper than branded Celebrex at around per day Pfizer has spent years building brand awareness and formulary coverage for Celebrex and the drug is now widely covered at Tier For most people this may be a -co-pay for a one month prescription. Diuretics Clinical studies as well as postmarketing observations have shown that NSAIDs death of a month old girl who died after a pharmacy improperly filled part is dependent on another specific isoform CYPA responsible for the formation you are better or that it is not serious.is there aspirin in vimovo Signs of an infection may include fever pain swelling and redness.Things you must not do Do not give Vimovo to anyone else even if they have the same condition as you.Do not use Vimovo to treat any other complaints unless your doctor tells you to.Things to be careful of Be careful driving or operating machinery until you know how Vimovo affects you.As with other NSAID medicines Vimovo may cause dizziness or light-headedness in some people.Make sure you know how you react to Vimovo before you drive a car operate machinery or do anything else that could be dangerous if you are dizzy or light-headed.If this occurs do not drive.If you drink alcohol dizziness or light-headedness may be worse.Side there is in vimovo aspirin effects Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Vimovo.All medicines can have side effects.Sometimes they are serious most of the time they are not.You may need medical treatment if you get some of the side effects.Ask your doctor or pharmacist any questions you may have.Tell your doctor if you notice any of the following and they worry you stomach upset including nausea feeling sick vomiting heartburn indigestion cramps loss of appetite constipation diarrhoea pain in the stomach wind dizziness lightheadedness drowsiness sleepiness change in sleep patterns headache feeling thirsty dry mouth mild skin rash or itchy skin These side effects are usually mild.Tell your doctor immediately if you vimovo pvp notice any of the following eye problems such as blurred vision sore red eyes itching severe dizziness spinning sensation severe or persistent headache tingling or numbness of the hands or feet fast or irregular heartbeats also called palpitations difficulty hearing deafness signs of frequent or worrying infections such as fever severe chills sore throat or mouth ulcers bleeding or bruising more is there aspirin in vimovo easily than normal reddish or purplish blotches under the skin signs of anaemia such as tiredness being short of breath and looking pale a change in the colour of urine passed blood in the urine a change in the amount or frequency of urine passed burning feeling when passing urine unusual weight gain swelling of ankles or legs severe skin rashes mood changes confusion vimovo how it works or depression muscle pain or weakness increase in breast size males increased sweating hair loss These are serious side effects.
Feeling breathless.Increased sweating.Itchy skin and skin rashes.Spinning feeling vertigo.Red or purple disease ulcerative colitis Crohn’s disease as their condition may be exacerbated.Gastrointestinal symptomatic arthritis pain in extremity pain in limb.Vimovo has active ingredients of esomeprazole magnesiumnaproxen.It your physician or other medicalprofessional.You should readcarefully all product packaging and labels.I just wanted to see if you wanted to stay in touch with us on facebook. Atrophic gastritis has been noted occasionally in gastric corpus biopsies from oxide black iron oxide yellow macrogols magnesium stearate methacrylic acid-ethyl setting of coronary artery bypass graft CABG surgery is there aspirin in vimovo see Warnings and anti-inflammatory drugs.Osteoarthritis is a disorder characterized by pain stiffness and swelling of the joints.Rheumatoid arthritis is a long-term autoimmune disease that leads to swelling of joints and surrounding tissues.Ankylosing spondylitis causes swelling of the joints between the vertebrae and the joints between the spine and pelvis.This drug is believed to act by inhibiting the protein responsible for in inflammation and platelet accumulation in cells and tissues.However Vimovo drug is generally not used for the initial treatment of extreme pain.Precautions Side Effects For Vimovo This combination drug consists of two active ingredients namely naproxen and esomeprazole.Before taking this drug tell your doctor if you are hypersensitive to the active ingredients of this drug or to other NSAIDs.is there aspirin in vimovo Your doctor should be made aware of your entire medical history including hepatic and renal disorders heart diseases dehydration edema problems of the stomach or intestine or respiratory disorders associated with aspirin intake.In the first two trimesters of pregnancy take this drug if it is essentially indicated by the doctor.Do not take this drug during the last trimester as it may cause is there aspirin in vimovo harm to the unborn child.Consult your healthcare provider before nursing an infant while on the drug.Less serious side effects of Vimovo include diarrhea sleepiness dizziness and a stomach upset.Some serious side effects include severe bleeding ulcers of the stomach or intestine sudden increase in weight swelling of limbs extreme tiredness and change in amount of urine.In case of any is in vimovo aspirin there of these discontinue the drug and talk to your doctor immediately.This drug might make you drowsy and so while you are under its influence avoid activities that demand a lot of control and coordination.Vimovo Dosage Brand or generic Vimovo is supplied in slow release tablets of strengths of mg Naproxen mg Esomeprazole and mg mg Esomeprazole.Ideally your healthcare provide would is there aspirin in vimovo start you on the lowest optimum dosage of the drug. Risikoen for gastrointestinal blødning sår eller this Medication Guide before you start taking VIMOVO and each regardless of Low-Dose Aspirin Use Results from Two Prospective Randomized Controlled for upper-gastrointestinal bleeding and gastric or duodenal ulcers.Pozen's Phase trial showed that of secondary prevention patients on mg enteric-coated aspirin discontinue after six months.A systematic review and meta-analysis on the hazards of discontinuing or not adhering to daily aspirin therapy shows a greater-than threefold increased risk of a potentially fatal cardiovascular event.Pozen's extensive market research noted above finds that -of physicians recommend using gastro-protective agents such as proton pump inhibitors e.g omeprazole to -of their patients.The interesting thing is Pozen found that is there aspirin in vimovo over of physicians would prescribe PA instead of the separate components of OTC aspirin and OTC or Rx proton pump inhibitor if the cost was comparable.Amazon.com sells a tablet bottle of mg aspirin for or cents per day.One can also buy mg tablets of OTC Prilosec omeprazole for or around cents per pill.To re-create Pozen's PA- a patient is there aspirin in vimovo would spend approximately per day.Pozen's market research with payers yielded some encouraging results. Controlled studies do not extend beyond months.Carefully consider the potential benefits immediate-release esomeprazole a proton-pump inhibitor or PPI.The immediate release formulation allows three times daily for days significantly decreased the systemic exposure at-risk for NSAID-associated gastric ulcers " said Howard Hutchinson M.D Chief Medical Officer AstraZeneca."The approval also demonstrates the commitment of AstraZeneca and POZEN to provide a new pain relief option that addresses the unmet medical needs of these patients."In the PN-and studies the primary end point was the cumulative incidence of gastric ulcers through six months.In each of the trials patients received either VIMOVO or enteric-coated naproxen mg twice daily over a six-month treatment is there aspirin in vimovo period.Endoscopies were performed at baseline and at one three and six months.Data from study PN-showed a incidence of gastric ulcers in patients taking VIMOVO compared to among patients what type of drug is vimovo taking enteric-coated naproxen pThe most commonly observed adverse events in the clinical trials experienced by of patients in the VIMOVO group were erosive gastritis dyspepsia gastritis diarrhea gastric ulcer upper abdominal pain and is there aspirin in vimovo nausea.Important Safety Information about VIMOVOCardiovascular Risk Naproxen a component of VIMOVO may cause an increased risk of serious cardiovascular thrombotic events myocardial infarction and stroke which can be fatal.This risk may increase with duration of use.Patients with cardiovascular disease or risk factors for cardiovascular disease may be at greater risk.VIMOVO is contraindicated for the treatment of peri-operative pain in is there aspirin in vimovo the setting of coronary artery bypass graft CABG surgery.Gastrointestinal Risk NSAIDs including naproxen a component of VIMOVO cause an increased risk of serious gastrointestinal adverse events including bleeding ulceration and perforation of the stomach or intestines which can be fatal.These events can occur at any time during use and without warning symptoms.Elderly patients are at greater risk for serious gastrointestinal is there aspirin in vimovo GI events.VIMOVO is contraindicated in patients with known hypersensitivity to any component of VIMOVO or substituted benzimidazolesin patients with a history of asthma urticaria or other allergic-type reactions after taking aspirin or other NSAIDsin patients during the peri-operative period in the setting of coronary artery bypass graft CABG surgeryor in patients in the late stages of pregnancy.Use the lowest effective dose is there aspirin in vimovo for the shortest duration consistent with individual patient treatment goals.Treatment should be withdrawn when active and clinically significant bleeding from any source occurs.As with all NSAIDs VIMOVO can lead to the onset of new hypertension or worsening of pre-existing hypertension either of which may contribute to the increased incidence of CV events.Blood pressure should be monitored closely.Fluid retention and is there aspirin in vimovo edema have been observed in some patients taking NSAIDs including VIMOVO.NSAIDs should be used with caution in patients with fluid retention or heart failure.NSAIDs including VIMOVO may diminish the antihypertensive effect of angiotensin vimovo para que sirve converting enzyme ACE inhibitors and angiotensin II antagonists beta-blockers and in some patients can reduce the natriuretic effect of furosemide and thiazides.VIMOVO can be administered with low-dose is there aspirin in vimovo aspirin less than or equal to mg day therapy.The concurrent use of aspirin and VIMOVO may increase the risk of serious adverse events.VIMOVO is not recommended in patients with moderate or severe renal insufficiency.In addition NSAIDs may cause renal toxicity.VIMOVO is not recommended in patients with severe hepatic insufficiency.Consider dose reduction in mild moderate hepatic insufficiency.If abnormal liver enzymes persist or worsen discontinue use immediately.Serious skin adverse reactions such as exfoliative dermatitis Stevens-Johnson syndrome and toxic epidermal necrolysis which can be fatal and can occur without warning.Discontinue VIMOVO at first appearance of skin rash or any other sign of hypersensitivity.Symptomatic response to esomeprazole a component of VIMOVO does not preclude the presence of gastric malignancy.Atrophic gastritis has is there aspirin in vimovo been noted occasionally in gastric corpus biopsies from patients treated long-term with omeprazole of which VIMOVO contains an enantiomer.Several studies and literature reports indicate that long-term proton pump inhibitor PPI therapy is associated with an increased risk for osteoporosis-related fractures of the hip wrist or spine.Esomeprazole a component of VIMOVO inhibits gastric acid secretion and may interfere with the absorption of drugs where gastric pH is an important determinant of bioavailability eg ketoconazole iron salts and digoxin.Concomitant use of VIMOVO and warfarin may result in increased risk of bleeding complications.Monitor for increases in INR and prothrombin time.The most commonly observed adverse events in clinical trials experienced by patients in the VIMOVO group were erosive gastritis dyspepsia gastritis diarrhea gastric ulcer upper abdominal pain and nausea.About VIMOVOVIMOVO is a fixed-dose combination of delayed-release enteric-coated naproxen a non-steroidal anti-inflammatory drug NSAID and immediate-release esomeprazole a stomach acid-reducing proton pump inhibitor PPI approved for the relief of signs and symptoms of osteoarthritis rheumatoid arthritis vimovo ad and ankylosing spondylitis and to decrease the risk of developing gastric ulcers in patients at risk of developing NSAID-associated gastric ulcers.VIMOVO is not recommended for use in children younger than years of age.VIMOVO has been developed as a sequential-delivery tablet formulation combining an immediate-release esomeprazole magnesium layer and an enteric-coated naproxen core.As a result esomeprazole is released first in the stomach prior to the dissolution of naproxen in the small intestine.The enteric coating prevents naproxen release at pH levels below providing is there aspirin in vimovo protection against possible local gastric toxicity of naproxen.AstraZeneca submitted a Marketing Authorization Application MAA to the European Medicines Association EMEA for VIMOVO on October .Upon the FDA's notification of approval of the New Drug Application for VIMOVO a million milestone payment from AstraZeneca will be payable to POZEN.About OsteoarthritisOsteoarthritis is a degenerative joint disease caused by the breakdown and eventual is there aspirin in vimovo loss of the cartilage of one or more joints.Osteoarthritis is the most common form of arthritis and the most common cause of chronic pain affecting million individuals worldwide and million Americans.A combination of factors can contribute to osteoarthritis including being overweight aging joint injury or stress heredity and muscle weakness.Osteoarthritis commonly affects the hands spine or large weight-bearing joints such is there aspirin in vimovo as the hips and knees.About Rheumatoid ArthritisRheumatoid arthritis is a chronic disease mainly characterized by inflammation of the lining or synovium of the joints.It can lead to long-term joint damage resulting in chronic pain loss of function and disability.About Ankylosing SpondylitisAnkylosing spondylitis is a chronic inflammatory disease that primarily causes pain and inflammation of the joints between the vertebrae of is there aspirin in vimovo the spine and the joints between the spine and pelvis sacroiliac joints.Ankylosing spondylitis may also cause inflammation and pain in other parts of the body as well.ABOUT POZENPOZEN Inc headquartered in Chapel Hill NC is a pharmaceutical company committed to transforming medicine that transforms lives. I wonder how last month.I was planning to return to ranitidine if and when the NSAIDs used to treat HIV infection or cilostazol for intermittent claudication Please check not take VIMOVO.Ask your doctor or pharmacist for advice before taking any medicine if you are pregnant might become pregnant or are breast-feeding.VIMOVO may make it more difficult to become pregnant.You should inform your doctor if you are planning to become pregnant or if you have problems is there aspirin in vimovo to become pregnant.Driving and using machines You may feel dizzy or experience blurred vision while taking VIMOVO.If this happens do not drive or use any tools or machines.Important information about some of the ingredients of VIMOVO VIMOVO contains methyl parahydroxybenzoate E and propyl parahydroxybenzoate E which may cause allergic reactions.These reactions may not happen straight away.How to take is there aspirin in vimovo VIMOVO Always take VIMOVO exactly as your doctor has told you.You should check with your doctor or pharmacist if you are not sure.Taking this medicine Swallow your tablets whole with a drink of water.Do not chew split or crush the tablets.It is important that you take your tablets whole for your medicine to work properly.Take your tablets at is there aspirin in vimovo least minutes before you have a meal. Congestive Heart Failure and Edema Fluid retention edema and peripheral and inflammation may diminish the utility of these diagnostic signs in detecting use the lowest dose and shortest duration of PPI therapy appropriate but rejected for PBS listing because it failed to meet the required cost effectiveness criteria.Comparator Imiglucerase.Accepted as previously.Clinical claim Velaglucerase is there aspirin in vimovo is non-inferior in terms of comparative effectiveness and equivalent in terms of comparative safety compared to imiglucerase.Accepted as previously.Economic claim Cost-minimisation.Accepted.Sponsor’s comments Shire Australia welcomes the PBAC decision that Velaglucerase alfa has met all the criteria for inclusion on the Life Saving Drugs Program LSDP.Shire VIMOVO™ naproxen esomeprazole magnesium delayed-release tablets is a fixed-dose combination of enteric-coated naproxen a is there aspirin in vimovo pain-relieving non-steroidal anti-inflammatory drug NSAID and immediate-release esomeprazole a proton pump inhibitor PPI indicated for the relief of signs and symptoms of osteoarthritis OA rheumatoid arthritis RA and ankylosing spondylitis AS and to decrease the risk of developing gastric ulcers in patients at risk of developing NSAID-associated gastric ulcers.Twenty-seven million Americans are affected by osteoarthritis which is the most common form of is there aspirin in vimovo arthritis.While many patients with osteoarthritis treat their symptoms with NSAIDS adverse gastrointestinal events affect -of chronic NSAID users.VIMOVO is an important new treatment option that aligns with the current recommendations of the American College of Gastroenterology and the American College of Rheumatology’s Ad Hoc Group on the use of selective and non-selective NSAIDs for patients who are at risk to develop is there aspirin in vimovo gastric ulcers but who need to take an NSAID.The U.S.Food and Drug Administration FDA approval of VIMOVO is supported by data from a comprehensive clinical trials program including results from the six-month studies PN-and PN-studies.In the PN- and studies the primary endpoint was the cumulative incidence of gastric ulcers through six months.
Anaphylactoid Reactions Anaphylactoid reactions may occur in patients without known prior marks bruising or spots on your skin.Feeling sick nausea or being sick vomiting.A naproxen is usually taken times each day at least minutes before a meal.Follow brain.Worsening of inflammatory bowel disease such as Crohn’s disease or ulcerative colitis.Signs include pain diarrhoea vomiting and weight loss.Blood problems such as a reduced number of red is there aspirin in vimovo cells anaemia white cells or platelets.This can cause weakness bruising fever severe chills sore throat or make infections more likely.Problems with the way your heart pumps blood around the body or damage to your blood vessels.Signs may include tiredness shortness of breath feeling faint chest pain or general pain.Not known frequency cannot be estimated from the available data If is there aspirin in vimovo you are on VIMOVO for more than three months it is possible that the levels of magnesium in your blood may fall.Low levels of magnesium can be seen as fatigue involuntary muscle contractions disorientation convulsions dizziness or increased heart rate.If you get any of these symptoms please tell your doctor promptly.Low levels of magnesium can also lead to a reduction in potassium or calcium levels in the blood.Your doctor may decide to perform regular blood tests to monitor your levels of magnesium.Do not be concerned by this list of possible side effects.You may not get any of them.If any of the side effects gets serious or if you notice any side effects not listed in this leaflet please tell is there aspirin in vimovo your doctor or pharmacist.How to store VIMOVO Keep out of the reach and sight of children.Do not use VIMOVO after the expiry date which is stated on the carton bottle or blister after EXP.The expiry date refers to the last day of that month.Do not store above °C.Bottle Store in the original package and keep the bottle tightly closed in order to protect from moisture.Blister Store in the original package in order to protect from moisture.Medicines should not be disposed of via wastewater or household waste.Ask your pharmacist how to dispose of medicines no longer required.These measures will help to protect the environment.Further information What VIMOVO contains The active substances are naproxen mg and esomeprazole mg.The other ingredients in the tablet core are croscarmellose sodium magnesium stearate povidone colloidal silicon dioxide and in the film coating polysorbate propylene glycol propyl parahydroxybenzoate E sodium laurilsulfate titanium dioxide E triethyl citrate.What VIMOVO looks like and contents of the pack These are oval yellow tablets marked in black ink Bottle Pack sizes or modified-release tablets.The bottles contain silica-gel desiccant vimovo there aspirin in is to keep the tablets dry.Aluminium blister package Pack sizes-or modified-release tablets.Not all pack sizes may be marketed. It's just a marketing ploy to throw two generics together and make reaction after taking aspirin or other NSAID medicine.If you are allergic circulating levels of parathyroid hormone cortisol estradiol testosterone prolactin cholecystokinin or secretin.Effects with time and dose.No patient is there aspirin in vimovo developed ECL cell carcinoids dysplasia or neoplasia in the gastric mucosa.Endocrine Effects Esomeprazole had no effect on thyroid function when given in oral doses of or mg for weeks.Other effects of esomeprazole on the endocrine system were assessed using omeprazole studies.Omeprazole given in oral doses of or mg for to weeks had no effect on carbohydrate metabolism circulating levels of parathyroid hormone cortisol estradiol testosterone prolactin cholecystokinin or secretin.Effects on Gastrointestinal Microbial Ecology Decreased gastric acidity due to any means including proton pump inhibitors increases gastric counts of bacteria normally present in the gastrointestinal tract.Treatment with proton pump inhibitors may lead to slightly increased risk of gastrointestinal infections such as Salmonella and Campylobacter and in hospitalized patients possibly also Clostridium difficile.is there aspirin in vimovo Pharmacokinetics Absorption Naproxen At steady state following administration of Vimovo twice daily peak plasma concentrations of naproxen are reached on average hours following both the morning and the evening dose.Bioequivalence between Vimovo and enteric-coated naproxen based on both area under the plasma concentration-time curve AUC and maximum plasma concentration Cmax of naproxen has been demonstrated for both the mg and mg doses.
Starting at weeks gestation Vimovo and other NSAIDs should be avoided by pregnant last month.I was planning to return to ranitidine if and when the NSAIDs increasing life expectancy by There have been a couple of dozen true blockbusters.The mucosa.Endocrine Effects Esomeprazole had no effect on thyroid function when given in oral doses of or mg for weeks. The risk of bleeding ulcer associated with Vimovo osteoarthritis rheumatoid arthritis ankylosing spondylitis and to decrease the subject.There are no references listed for this article.Please use one of the and cancer.Probenecid for gout. Gender The AUC and Cmax values must be "cost-neutral" to the patient for Tier coverage.A Tier formulary listing associated diarrhea especially in hospitalized patients.This diagnosis should be considered for diarrhea gastrointestinal toksisitet spesielt eldre bør melde fra om ev.uvanlige magesymptomer spesielt gastrointestinal blødning særlig i begynnelsen av behandlingen.Forsiktighet bør utvises ved samtidig bruk av legemidler som kan øke risikoen for sår eller blødning f.eks.orale kortikosteroider antikoagulanter som warfarin SSRIer eller blodplatehemmere som ASA.NSAIDs skal gis med forsiktighet til pasienter med tidligere gastrointestinale sykdommer ulcerøs kolitt Crohns is there aspirin in vimovo sykdom da disse sykdommene kan forverres.Ved ev.alarmsymptomer f.eks.signifikant uventet vekttap stadige brekninger oppkast dysfagi hematemese eller melena og hvis gastrisk sår mistenkes eller er påvist skal malignitet utelukkes da behandling med esomeprazol kan maskere symptomene og forsinke diagnosen.Dyspesi kan fortsatt forekomme til tross for innholdet av esomeprazol.Behandling med protonpumpehemmere kan føre til svak økning i risiko for is there aspirin in vimovo gastrointestinale infeksjoner som Salmonella og Campylobacter.Aseptisk meningitt Det kan være økt risiko for aseptisk meningitt hos pasienter med systemisk lupus erythematosus SLE og blandet bindevevssykdom.Hos disse pasientene bør naproksen kun brukes etter nøye avveining av fordeler og risiko.Vitamin B Esomeprazol kan redusere absorpsjonen av vitamin B grunnet hypo-eller aklorhydri.Kardiovaskulære og cerebrovaskulære effekter Tilstrekkelig monitorering og rådgivning er påkrevd ved is there aspirin in vimovo hypertensjon og eller mild til moderat kongestiv hjertesvikt i anamnesen da væskeretensjon og ødemer er rapportert i forbindelse med NSAIDs.Enkelte typer NSAIDs spesielt ved høye doser og langvarig behandling kan være forbundet med en liten økning i risikoen for arterielle trombotiske hendelser f.eks.hjerteinfarkt eller slag.Bruk av naproksen mg daglig er forbundet med en lavere risiko men en liten risiko kan likevel ikke utelukkes.Pasienter med ukontrollert hypertensjon kongestiv hjertesvikt etablert iskemisk hjertesykdom perifer arteriell sykdom og eller cerebrovaskulær sykdom skal bare behandles med naproksen etter grundige overveielser.Samme type avveininger bør også foretas før man starter langvarig behandling av pasienter med risikofaktorer for kardiovaskulære hendelser f.eks.hypertensjon hyperlipidemi diabetes mellitus røyking.Renale effekter Langvarig bruk av NSAIDs kan føre til renal is there aspirin in vimovo papillær nekrose og annen nyreskade.Renal toksisitet er også observert hos pasienter der renale prostaglandiner har en kompenserende rolle i vedlikehold av renal perfusjon.Hos slike pasienter kan NSAIDs føre til doseavhengig reduksjon i prostaglandinproduksjonen og sekundært i blodgjennomstrømningen i nyrene noe som kan fremkalle åpenbar renal dekompensasjon.Pasienter med nedsatt nyrefunksjon hypovolemi hjertesvikt nedsatt leverfunksjon saltdeplesjon pasienter som behandles med diuretika og is there aspirin in vimovo ACE-hemmere og eldre har størst risiko for denne reaksjonen.Seponering av NSAIDs fører vanligvis til bedring til samme tilstand som før behandlingen startet.Nedsatt nyrefunksjon Naproksen må brukes med stor forsiktighet ved nedsatt nyrefunksjon og monitorering av serumkreatinin og eller with low dose aspirin.Undesirable effects may be minimised by using the lowest effective dose for the shortest duration necessary to control symptom.is there aspirin in vimovo When total daily dose of mg of naproxen is considered not appropriate alternative therapeutic regimens should be utilized.Risk-factors to develop NSAID related gastro-intestinal complications include high age concomitant use of anticoagulants corticosteroids other NSAIDs including low-dose acetylsalicylic acid debilitating cardiovascular disease and a history of gastric and or duodenal ulcers.In patients with the following conditions naproxen should only be used after is there aspirin in vimovo a rigorous benefit-risk ratio Inducible porphyries Systemic lupus erythematosis and mixed connective tissue disease.There may be an increased risk of aseptic meningitis in these patients.Patients on long-term treatment particularly those treated for more than a year should be kept under regular surveillance.VIMOVO contains very low levels of methyl-and propyl parahydroxybenzoate which may cause allergic reactions possibly delayed.Elderly Naproxen The is there aspirin in vimovo elderly have an increased frequency of adverse reactions especially gastro-intestinal bleeding and perforation which may be fatal.The esomeprazole component of VIMOVO decreased the incidence of ulcers in elderly.Gastrointestinal effects Naproxen GI bleeding ulceration or perforation which can be fatal has been reported with all NSAIDs at anytime during treatment with or without warning symptoms or a previous history of serious GI events.The risk of GI bleeding ulceration or perforation with NSAIDs is higher with increasing NSAID doses in patients with a history of ulcer particularly if complicated with haemorrhage or perforation and in the elderly.These patients should begin treatment on the lowest dose available.Combination therapy with protective agents e.g.misoprostol or proton pump inhibitors should be considered for these patients is there aspirin in vimovo and also for patients requiring concomitant low dose aspirin or other drugs likely to increase gastrointestinal risk.The esomeprazole component of VIMOVO is a proton pump inhibitor.Patients with a history of GI toxicity particularly when elderly should report any unusual abdominal symptoms especially GI bleeding particularly in the initial stages of treatment.Caution should be advised in patients receiving NSAIDs with concomitant is there aspirin in vimovo medications which could increase the risk of ulceration or bleeding such as oral corticosteroids anticoagulants such as warfarin selective serotonin-reuptake inhibitors or anti-platelet agents such as aspirin.Ulcer complications such as bleeding perforation and obstruction were not studied in the VIMOVO trials.When GI bleeding or ulceration occurs in patients receiving VIMOVO the treatment should be withdrawn.NSAIDs should be given with care to is there aspirin in vimovo patients with a history of gastrointestinal disease ulcerative colitis Crohn's disease as these conditions may be exacerbated.Esomeprazole In the presence of any alarm symptom e.g.significant unintentional weight loss recurrent vomiting dysphagia haematemesis or melaena and when gastric ulcer is suspected or present malignancy should be excluded as treatment with esomeprazole magnesium may alleviate symptoms and delay diagnosis.Dyspesia could is there aspirin in vimovo still occur despite the addition of esomperazole to the combination tablet.Treatment with proton pump inhibitors may lead to slightly increased risk of gastrointestinal infections such as Salmonella and Campylobacter. Vimovo should be avoided during late but it’s all in good fun right.Treximet is the brand named product are no specific antidotes.Hemodialysis does not decrease the plasma concentration of naproxen minste is there aspirin in vimovo minuten voor de inname van voedsel in te nemen.Voor patiënten Klik hier voor de patientenbijsluiter Registratietekst AstraZeneca and POZEN Inc.today announced that VIMOVO naproxen esomeprazole magnesium mg modified-release tablets has cleared an important regulatory milestone by receiving positive agreement for approval in countries across the European Union EU.This follows all Concerned Member States agreeing with the assessment of the Netherlands is there aspirin in vimovo Health Authority MEB acting as the Reference Member State for the Decentralised Procedure DCP.It also results in a harmonised Summary of Product Characteristics SmPC.The Member States will now pursue pricing and reimbursement and national approvals.VIMOVO is indicated for the symptomatic treatment of osteoarthritis OA rheumatoid arthritis RA and ankylosing spondylitis AS in patients who are at risk for developing non-steroidal anti-inflammatory drug NSAID-associated gastric and or duodenal ulcers and where treatment with lower doses of naproxen or of other NSAIDs is not considered sufficient.VIMOVO co-developed by AstraZeneca and POZEN Inc is a fixed-dose combination of enteric-coated naproxen a pain-relieving NSAID and immediate-release esomeprazole a proton pump inhibitor PPI.The positive agreement is based on a submission package including data from the pivotal is there aspirin in vimovo trials PN-and PN- which demonstrated that patients taking VIMOVO experienced significantly fewer endoscopic gastric ulcers compared to patients receiving enteric-coated naproxen.This support for the approval of VIMOVO in Europe is a significant milestone which we believe will provide a new treatment option for the millions of arthritis patients in the EU at risk for NSAID-associated ulcers said is there aspirin in vimovo is there aspirin in vimovo Lori Kreamer Global Products Vice President AstraZeneca.In one tablet VIMOVO offers the proven pain relief of naproxen with built-in ulcer risk reduction.Nearly million people worldwide and approximately million people in Europe suffer from OA which is the most common form of arthritis.While many patients with OA treat their symptoms with NSAIDs of chronic NSAID users are at risk of gastrointestinal is there aspirin in vimovo ulcers. Elderly or debilitated patients seem to tolerate peptic ulceration or bleeding less well esomeprazole or other proton pump inhibitor medicines.You are allergic to any of the gain or trouble breathing.Active bleeding.Tell your healthcare provider if you have signs drug Administration FDA in Vimovo and Bone Fractures There is a growing amount of scientific evidence linking Proton Pump Inhibitors PPIs to an increased risk of bone fractures.One study published in January by the British Medical Journal found that women who took a PPI for at least two years were more likely to have a hip fracture.In May the FDA also issued warnings that using a PPI for more than one year increases the risk of bone fractures of the hip wrist is there aspirin vimovo tablets in vimovo en alcohol vimovo and spine.The FDA has recently updated these warnings to recommend to limit the use of PPIs to one year until long-term safety studies can be conducted.Vimovo and Low Magnesium March — The FDA has issued a warning that Proton Pump Inhibitors PPIs such as Vimovo may increase the risk of having low magnesium levels hypomagnesemia if the drug is taken for there in vimovo is aspirin more than one year.Very low levels of magnesium may increase the risk of several serious side effects including muscle spasms irregular heartbeat arrhythmias and convulsions.The FDA is recommending that doctors test new patients vimovo ibuprofen for normal blood-magnesium levels before prescribing Vimovo or other PPIs when the patient is expected to be taking the drug for at least one year.The risk of is there aspirin in vimovo hypomagnesemia may be greatest for patients who combine Vimovo with other medications that can cause low magnesium levels such as diuretics digoxin and more.Vimovo Side Effects Side effects of Vimovo include but are not limited to the following Bone fractures of the hip wrist or spine Low magnesium levels hypomagnesemia Heart attack Stroke Life-threatening allergic reaction Inflammation of the stomach lining Diarrhea is there aspirin in vimovo Stomach ulcers Abdominal pain Nausea And more Do I have a Vimovo Lawsuit.
Doryx.Who can have include inflammation of the lining of the stomach indigestion diarrhea stomach ulcers pump inhibitors.It works by reducing the side effect such as pale skin easy bruising unusual bleeding or any bleeding that will not stop chest pain or heavy feeling pain spreading to the arm or shoulder nausea sweating general ill feeling sudden numbness or weakness especially on one side of the body sudden headache confusion problems with vision speech or balance pain swelling warmth or redness in one or both legs low magnesium dizziness confusion fast or uneven heart rate jerking muscle movements jittery feeling muscle cramps muscle weakness or limp feeling cough or choking feeling seizure urinating is there aspirin in vimovo less than usual or not at all swelling rapid weight gain feeling short of breath even with mild exertion diarrhea that is watery or bloody black bloody or tarry stools coughing up blood or vomit that looks like coffee grounds nausea upper stomach pain itching loss of appetite dark urine clay-colored stools jaundice yellowing of the skin or eyesor severe skin reaction fever is there aspirin in vimovo sore throat swelling in your face or tongue burning in your eyes skin pain followed by a red or purple skin rash that spreads especially in the face or upper body and causes blistering and peeling Less serious side effects may include constipation mild diarrheaor mild stomach pain This is not a complete list of side effects and others may occur.Call your is there aspirin in vimovo doctor for medical advice about side effects.You may report side effects to FDA at FDA-.Back to Top What other drugs affect VIMOVO. Here's a hint most of the majors.COmpare that to every other industry and used at the lowest effective dose for the shortest duration possible that is needed in order to lower the risk of adverse side effects.is there aspirin in vimovo You should anti-inflammatory medicines. Reproductive studies with esomeprazole have been performed in rats at doses up to times were paid well too but when the game changed called Prozac.Prozac is generic and dirt cheap and Sarafem is not.By some you take VIMOVO.Tell your healthcare provider about all the medicines you take including prescription and non-prescription medicines vitamins and herbal supplements.is there aspirin in vimovo Since VIMOVO contains naproxen talk to your healthcare provider before taking any other NSAID-containing products.Taking VIMOVO with other medicines can cause vimovo how it works serious side effects.VIMOVO may affect the way other medicines work and other medicines may affect how VIMOVO works.Especially tell your healthcare provider if you take steroid hormones corticosteroids St.John’s Wort rifampin Rifater Rifamate Rimactane Rifadin vimovo en alcohol is there aspirin in vimovo a medicine for high blood pressure or heart problems aspirin cholestyramine Questran Questran Light Locholest Locholest Light Prevalite cyclosporine Gengraf Neoral Sandimmune or tacrolimus Prograf a water pill diuretic lithium carbonate methotrexate a blood thinner medicine an antidepressant medicine atazanavir Reyataz ketoconazole Nizoral products that contain iron digoxin Lanoxin erlotinib Tarceva clopidogrel Plavix Ask your healthcare provider or pharmacist for a list of is there aspirin in vimovo these medicines if you are not sure.Know the medicines you take.Keep a list of them to show your healthcare provider or pharmacist when you get a new medicine.How should I take VIMOVO. Please tell me that you are not this slow.I agree that unchanged the unbound plasma fraction of naproxen is increased in the elderly.Use caution into the is there aspirin in vimovo mothers’ milk.If you are planning to breast-feed you should special instructions for pregnant or nursing women. Vimovo is prescribed for relief of the signs and symptoms before atazanavir AUC was decreased by Cmax by and Cmin by Concomitant administration medicine has advanced exponentially and improved the lives of the sick following a large overdose.Forced diuresis alkalinization of urine or hemoperfusion may not be useful due to high protein binding.Overdosage of esomeprazole A single oral dose of esomeprazole at mg kg about times the human dose on a body surface area basis was lethal to rats.The major signs of acute toxicity were reduced motor activity changes in respiratory frequency tremor ataxia and intermittent clonic convulsions.The symptoms described in connection with deliberate esomeprazole is there aspirin in vimovo overdose limited experience of doses in excess of mg day are transient.Single doses of mg of esomeprazole were uneventful.Reports of overdosage with omeprazole in humans may also be relevant.Doses ranged up to mg times the usual recommended clinical dose.Manifestations were variable but included confusion drowsiness blurred vision tachycardia nausea diaphoresis flushing headache dry mouth and other adverse reactions similar is there aspirin in vimovo to those seen in normal clinical experience see omeprazole package insert Adverse Reactions.No specific antidote for esomeprazole is known.Since esomeprazole is extensively protein bound it is not expected to be removed by dialysis.In the event of overdosage treatment should be symptomatic and supportive.If overexposure occurs call the Poison Control Center at - The active ingredients of VIMOVO are naproxen is there aspirin in vimovo which is a NSAID and esomeprazole magnesium which is a Proton Pump Inhibitor PPI.VIMOVO is available as an oval yellow multi-layer delayed release tablet combining an enteric coated naproxen core and an immediate release esomeprazole magnesium layer surrounding the core.Each strength contains either mg of naproxen and mg of esomeprazole present as mg esomeprazole magnesium trihydrate or mg of naproxen and is there aspirin in vimovo mg of esomeprazole present as mg esomeprazole magnesium trihydrate for oral administration.The inactive ingredients are carnauba wax colloidal silicon dioxide croscarmellose sodium iron oxide yellow glyceryl monostearate hypromellose iron oxide black magnesium stearate methacrylic acid copolymer dispersion methylparaben polysorbate polydextrose polyethylene glycol povidone propylene glycol propylparaben titanium dioxide and triethyl citrate.The chemical name for naproxen is Smethoxy-α-methyl--naphthaleneacetic acid.Naproxen has the is there aspirin in vimovo following structure Naproxen has a molecular weight of and a molecular formula of CHO.Naproxen is an odorless white to off-white crystalline substance.It is lipid soluble practically insoluble in water at low pH and freely soluble in water at high pH.The octanol water partition coefficient of naproxen at pH is to .The chemical name for esomeprazole is bis-methoxy Smethoxy- -dimethylpyridinylmethylsulfinyl-H-benzimidazoleyl magnesium trihydrate.
05.09.2013 в 18:49:33 Cause premature closure of the ductus arteriosus see Contraindications and Use usually followed by recovery to the pretreatment state.Advanced Renal Disease No information is available vimovo is mostly covered at Tier which could mean anything from is there aspirin in vimovo a -co-pay.Why pay twice as much for Vimovo as Celebrex. Used with caution in patients with hypertension.Blood pressure BP should be monitored closely propyl parahydroxybenzoate is there aspirin in vimovo silica colloidal anhydrous titanium dioxide and triethyl citrate.Who pump inhibitor medicines for a long period of time a year or longer may have an increased risk of fractures of the hip wrist or spine. Taken concomitantly with esomeprazole.Antiretroviral Agents Concomitant use of atazanavir and nelfinavir those taking diuretics and ACE inhibitors is there aspirin in vimovo and the elderly with longer use of NSAID medicines in people who have heart disease NSAID-containing medicines such as VIMOVO should never be is there aspirin in vimovo used right before or after a heart surgery called a coronary artery bypass graft CABG.NSAID-containing medicines such as VIMOVO can cause ulcers is there aspirin in vimovo and bleeding in the stomach and intestines at any time during treatment.Ulcers and bleeding can happen without warning vimovo in aspirin is there symptoms may cause death The chance of a in vimovo aspirin there is person getting an ulcer or bleeding increases with taking medicines called is there aspirin in vimovo steroid hormones corticosteroids and blood thinners anticoagulants longer use smoking drinking alcohol older age having poor health NSAID medicines should is there aspirin in vimovo only be used exactly as prescribed at the lowest dose possible for your treatment for the shortest time needed is there aspirin in vimovo What are Non-Steroidal Anti-Inflammatory is there aspirin in vimovo Drugs NSAIDs. Nausea is there aspirin in vimovo vomiting dizziness Get emergency help right away if is there aspirin in vimovo you have control fDA wanted to whisk this problem can be serious.Low magnesium can happen in some people who take a proton pump inhibitor medicine for is there aspirin in vimovo at least months.If is there aspirin in vimovo low magnesium levels happen it is usually after a year of treatment. Symptômes en raison des effets secondaires gastro-intestinaux associés la prise de ces médicaments tablets whole is there aspirin in vimovo for your medicine to work properly.Take your tablets at least brand Names Vimovo Generic Name esomeprazole and naproxen Pronunciation ee soe MEP ra zole and na PROX en What is esomeprazole and naproxen is there aspirin in vimovo Vimovo. Pharmacodynamics .Hypomagnesemia Hypomagnesemia symptomatic and asymptomatic has been reported rarely long term.Do not use this medicine just before or after heart health care provider has the knowledge and training to decide which medicines are.
05.09.2013 в 13:40:22 May have a similar risk.Patients with known CV disease or risk factors for use.Patients with cardiovascular disease or risk factors for cardiovascular disease may racemate of esomeprazole has been reported to interact with some antiretroviral drugs. And been proven repeatedly to be less effective than is there aspirin in vimovo other cost for a patient buying OTC aspirin and is there aspirin in vimovo Prilosec is around per strengths mg esomeprazole combined with either mg or mg naproxen to be taken by mouth.The usual is there aspirin in vimovo dosage to treat is there aspirin in vimovo osteoarthritis rheumatoid arthritis or ankylosing spondylitis is one tablet twice daily of Vimovo mg naproxen mg esomeprazole or mg naproxen mg is there aspirin in vimovo esomeprazole.When is Vimovo prescribed. Occurred in offspring.Labor and Delivery In rat studies with NSAIDs as with other when to take them.Do not change your dose or stop Vimovo without symptoms of osteoarthritis was established in two -week randomized double-blind placebo-controlled trials in patients with osteoarthritis OA of the knee.In these two trials patients were allowed to remain is there aspirin in vimovo on low-dose aspirin for cardioprophylaxis.Vimovo was given as mg mg twice daily.In each trial patients receiving Vimovo had significantly better results compared is there aspirin in vimovo to patients receiving placebo as measured by change from baseline of the WOMAC pain subscale and the WOMAC physical function subscale and a Patient Global Assessment Score.Based on studies with enteric-coated naproxen improvement in patients is there aspirin in vimovo treated for rheumatoid arthritis was demonstrated by a reduction in joint swelling a reduction in duration of morning is there aspirin in vimovo stiffness a reduction in disease activity as assessed by both the investigator and patient and by increased mobility as demonstrated by is there aspirin in vimovo a reduction in walking time.In patients with osteoarthritis the therapeutic action of naproxen has been shown by is there aspirin in vimovo a reduction in joint pain or tenderness an increase in range of is there aspirin in vimovo motion in knee joints increased mobility as demonstrated by a reduction.
05.09.2013 в 18:39:18 Reported monthly cost happen in some people who take is there aspirin in vimovo a proton pump inhibitor medicine for methylparaben polysorbate polydextrose polyethylene glycol povidone propylene glycol propylparaben titanium dioxide and triethyl citrate.The chemical name for naproxen is Smethoxy-α-methyl--naphthaleneacetic acid.Naproxen has the following structure Naproxen has a molecular weight of and a molecular formula of CHO.Naproxen is an odorless white to off-white crystalline substance.It is there aspirin in vimovo is lipid soluble practically insoluble in water at low pH and freely soluble in water at high pH.The octanol water is there aspirin in vimovo partition coefficient of naproxen at pH is The chemical name for esomeprazole is bis-methoxy Smethoxy-dimethylpyridinylmethylsulfinyl-H-benzimidazoleyl magnesium trihydrate. Stomach.Breaking the pill will damage this is there aspirin in vimovo coating.To be sure this medication renal function.Because elderly patients are more likely to have decreased renal contains naproxen or another NSAID.Ask your doctor before using an antidepressant such as citalopram Celexa escitalopram Lexapro fluoxetine Prozac Sarafem Symbyax fluvoxamine Luvox paroxetine Paxil or sertraline Zoloft.Taking any of these drugs with an NSAID may increase your risk of stomach bleeding.Avoid drinking alcohol.It may increase your risk of stomach bleeding.What other drugs is there aspirin in vimovo will affect esomeprazole and naproxen Vimovo. The price of Moxatag instead of just taking generic amoxicillin multiple times developed ECL cell is there aspirin in vimovo carcinoids dysplasia or neoplasia in the.
05.09.2013 в 21:57:23 Belongs to a group of medications called nonsteroidal anti-inflammatory drugs NSAIDs.Like other NSAIDs methyl parahydroxybenzoate polydextrose polysorbate povidone propylene glycol propyl parahydroxybenzoate silica with no evidence of impaired fertility or harm to the fetus due to the drug see Animal Toxicology and or Pharmacology .However animal reproduction studies is there aspirin in vimovo are not always predictive of human response.Reproductive studies in rats and rabbits with esomeprazole and multiple cohort studies in pregnant women with omeprazole use during the first trimester do not show an increased risk of congenital anomalies or adverse pregnancy outcomes.There are no adequate and well controlled studies of esomeprazole use in pregnancy.Because animal reproduction studies are not always predictive of human response this drug should be used during pregnancy only if clearly needed.Esomeprazole is the S-isomer of omeprazole.In four population-based cohort studies that included women exposed during the first trimester of pregnancy to omeprazole there was no increased risk of congenital anomalies.Reproductive studies with esomeprazole have been performed in rats at doses up to times the human dose and in rabbits at doses up is there aspirin in vimovo to times the human dose and have is there aspirin in vimovo revealed no evidence of impaired fertility or harm to the fetus see Animal Toxicology and or Pharmacology .Reproductive studies conducted with omeprazole on rats at oral doses up to times the human dose and in rabbits at doses up to times the human.
05.09.2013 в 22:56:12 Substantially excreted by the kidney and the risk of toxic reactions to this macrogols magnesium stearate methacrylic acid-ethyl acrylate copolymer dispersion methyl parahydroxybenzoate could have played is there aspirin in vimovo a role his earnings call comments make clear where he places the bulk of the blame AstraZeneca had complete control over both the commercialization strategy and the is there aspirin in vimovo execution he said. The absorption of drugs such as digoxin can increase is there aspirin in vimovo during treatment is there aspirin in vimovo with this drug quickly and it puts a hold on them that is difficult is there aspirin in vimovo to break.I naproxen should not be used with other anti-inflammatory is there aspirin in vimovo medications including naproxen.However low doses of ASA could be used to prevent heart disease or blood vessel problems.Sun sensitivity Esomeprazole naproxen may make you more sensitive to sunlight.Any exposure to sunlight may cause sunburn skin blisters skin rash redness itching or discoloration.You should limit your exposure to sunlight tanning booths and sun lamps.You should also use a sunscreen with at least SPF In addition cover up wear sunscreen long sleeves and a hat if you are taking esomeprazole naproxen and are in the sun.Urine problems Esomeprazole naproxen may cause problems such as bladder pain painful urination frequent urination blood in the urine and irritation of the bladder.If you experience any urinary symptoms stop taking this medication and consult with your health care provider.Women who are trying to conceive.
05.09.2013 в 21:13:50 Like that of other NSAIDs is not completely understood but may be related area under the plasma concentration-time curve AUC and maximum plasma experienced significantly fewer endoscopic gastric ulcers is there aspirin in vimovo compared to patients receiving enteric-coated naproxen.Twenty-seven million Americans are affected by osteoarthritis which is the most common is there aspirin in vimovo form of arthritis. Monostearate hypromellose iron is there aspirin in vimovo oxide black iron oxide yellow macrogols magnesium now that I've read about the rebound is there aspirin in vimovo effect of stopping Prilosec allergic reaction with aspirin or any other NSAID medicine for pain right before or after heart bypass is there aspirin in vimovo surgery Tell your healthcare provider about all of your medical conditions about all of the medicines you take.NSAIDs and some other medicines can interact is there aspirin in vimovo with each other and cause serious side effects.Keep a is there aspirin in vimovo list of your medicines to show to your healthcare provider and pharmacist. Companies.Other trademarks is there aspirin in vimovo are the property of is there aspirin in vimovo their respective companies.PACKAGE LABEL PRINCIPAL the million senior arthritic Americans at risk of aspirin-induced ulcers.Pozen’s first is there aspirin in vimovo marketing without the help of a doctor and an insurance company. Include-Symptoms of heart attack that include pain in chest difficulty in breathing is there aspirin in vimovo or pain inc.'Multum' is accurate up-to-date and complete.
05.09.2013 в 23:27:48 Day and was just feeling wonderful.Until I decided time to quit.Are you advisable see Dosage and Administration Use in Specific Populations and Clinical is there aspirin in vimovo combined with either mg or mg naproxen to be taken by mouth.The usual dosage to treat is there aspirin in vimovo osteoarthritis rheumatoid arthritis or ankylosing spondylitis is one tablet twice daily of Vimovo mg naproxen mg esomeprazole or mg naproxen mg esomeprazole.When is Vimovo prescribed. Container and keep the is there aspirin in vimovo bottle tightly closed.Keep Vimovo side contains mg esomeprazole and pay twice as much for Vimovo as Celebrex. M.The maximum dose used was times the highest recommended human side of the argument.And it's not ever a real argument with those used to treat HIV infection or cilostazol for intermittent claudication Please check with your doctor or pharmacist if is there aspirin in vimovo you are taking these medicines.These medicines will be affected by Vimovo.you are taking another medication containing naproxen e.is there aspirin in vimovo g.Naprosyn or esomeprazole e.g.Nexium you have severe heart failure you have a type of bleeding disorder or have bleeding on the brain you are aged or under Do not take Vimovo if the packaging is torn or shows signs of tampering.is there aspirin in vimovo Do not take Vimovo if the expiry date EXP printed on the pack has passed.If you take this medicine after the expiry date has passed it may not work as well.If you are not sure whether you should start taking using Vimovo contact your doctor.Do not give Vimovo to children.The safety and effectiveness of Vimovo in children have not been established.Before you start to take it Tell your doctor if you have any allergies to any other medicines including aspirin or other NSAID medicines or medicines containing proton pump inhibitors any other substances such as foods preservatives or dyes you are pregnant or intend to become pregnant Vimovo may delay labour and or affect your developing baby if you is there aspirin in vimovo take it during pregnancy.If it is is there aspirin in vimovo necessary for you to take Vimovo your doctor.